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Toshio Matsumoto Selected Research

Neoplasms (Cancer)

1/2021Reveromycin A, a novel acid-seeking agent, ameliorates bone destruction and tumor growth in multiple myeloma.
4/2020The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat.
11/2017TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects.
10/2015Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation.
1/2015Nationwide survey of fibroblast growth factor 23 (FGF23)-related hypophosphatemic diseases in Japan: prevalence, biochemical data and treatment.
1/2014Magnetically responsive smart nanoparticles for cancer treatment with a combination of magnetic hyperthermia and remote-control drug release.
6/2013Gold nanoparticle cluster-plasmon-enhanced fluorescent silica core-shell nanoparticles for X-ray computed tomography-fluorescence dual-mode imaging of tumors.
1/2013Superparamagnetic nanoparticle clusters for cancer theranostics combining magnetic resonance imaging and hyperthermia treatment.
2/2012Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate.
1/2012Inhibition of TACE activity enhances the susceptibility of myeloma cells to TRAIL.
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Toshio Matsumoto Research Topics

Disease

49Osteoporosis
02/2024 - 12/2002
25Multiple Myeloma
01/2021 - 09/2002
23Neoplasms (Cancer)
01/2021 - 06/2003
22Bone Resorption
01/2022 - 09/2002
13Atherosclerosis
01/2020 - 09/2002
8Osteomalacia
02/2024 - 10/2007
8Hypocalcemia
07/2019 - 12/2003
7Osteoporotic Fractures
02/2024 - 10/2011
7Fibrosis (Cirrhosis)
08/2023 - 08/2005
7Rickets (Rachitis)
01/2020 - 12/2003
7Carotid Artery Diseases
04/2016 - 06/2004
6Inflammation (Inflammations)
01/2022 - 08/2002
6Hypoparathyroidism
07/2019 - 04/2007
6Wrist Fractures
10/2014 - 10/2011
6Muscular Diseases (Myopathy)
07/2004 - 08/2002
5Hypercalcemia (Milk Alkali Syndrome)
11/2019 - 09/2005
5Cardiovascular Diseases (Cardiovascular Disease)
01/2018 - 10/2009
5Ischemia
01/2018 - 01/2005
5Insulin Resistance
12/2017 - 04/2004
5Hypertension (High Blood Pressure)
01/2014 - 01/2003
5Vascular Remodeling
01/2011 - 02/2004
5Mitochondrial Diseases (Mitochondrial Disease)
07/2004 - 02/2002
4Hypercalciuria
02/2024 - 04/2015
4Breast Neoplasms (Breast Cancer)
02/2024 - 12/2002
4Diabetes Mellitus
12/2021 - 06/2004
4Metabolic Bone Diseases (Osteopenia)
12/2020 - 01/2008
4Hypertrophy
04/2010 - 11/2003
3Hypophosphatemia
02/2024 - 12/2003
3Type 2 Diabetes Mellitus (MODY)
08/2023 - 01/2015
3Obesity
01/2023 - 04/2004
3Urolithiasis
01/2022 - 12/2012
3Body Weight (Weight, Body)
09/2021 - 02/2010
3Coronary Artery Disease (Coronary Atherosclerosis)
08/2015 - 09/2002
3Postmenopausal Osteoporosis
07/2012 - 01/2008
3Heart Failure
01/2012 - 10/2009
3Lymphoma (Lymphomas)
08/2010 - 12/2004
3Disease Progression
01/2010 - 06/2003
3Ophthalmoplegia (External Ophthalmoplegia)
12/2005 - 09/2002
2Prostatic Neoplasms (Prostate Cancer)
03/2024 - 12/2018

Drug/Important Bio-Agent (IBA)

16Diphosphonates (Bisphosphonates)IBA
01/2022 - 05/2002
13Biomarkers (Surrogate Marker)IBA
08/2023 - 07/2004
13Vitamin DFDA LinkGeneric
11/2020 - 06/2003
13eldecalcitol (ED 71)IBA
07/2020 - 09/2005
12alfacalcidolIBA
07/2020 - 07/2010
11MineralsIBA
12/2020 - 11/2004
8Phosphates (Orthophosphate)IBA
02/2024 - 10/2007
8CalciumIBA
02/2024 - 09/2006
8ThrombinFDA Link
08/2023 - 02/2004
8Heparin Cofactor IIIBA
08/2023 - 02/2004
7AndrogensIBA
03/2024 - 08/2005
7Parathyroid Hormone (Parathormone)IBA
02/2024 - 09/2006
7Collagen Type I (Type I Collagen)IBA
01/2022 - 01/2007
7DenosumabFDA Link
01/2021 - 07/2014
7Monoclonal AntibodiesIBA
02/2015 - 02/2006
6Androgen Receptors (Androgen Receptor)IBA
01/2023 - 11/2003
6GlucocorticoidsIBA
01/2021 - 01/2003
6hydroxide ionIBA
11/2020 - 12/2004
6Glucose (Dextrose)FDA LinkGeneric
12/2017 - 09/2003
6Adrenal Cortex Hormones (Corticosteroids)IBA
01/2011 - 08/2002
6AntibodiesIBA
01/2010 - 12/2003
6AntigensIBA
06/2009 - 11/2005
5YM 529IBA
07/2020 - 06/2009
5Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2018 - 01/2008
5Bortezomib (Velcade)FDA Link
06/2011 - 02/2007
4Calcium-Sensing ReceptorsIBA
02/2024 - 01/2013
4romosozumabIBA
05/2021 - 01/2017
4pitavastatin (itavastatin)FDA Link
01/2018 - 01/2008
4Cholecalciferol (Vitamin D3)FDA Link
11/2015 - 10/2011
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2013 - 12/2002
4Bone Marrow Stromal Antigen 2IBA
10/2010 - 12/2008
4Angiotensin IIIBA
04/2010 - 08/2005
4Transforming Growth Factor beta (TGF-beta)IBA
03/2010 - 01/2008
4Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA
04/2008 - 09/2002
3Hormones (Hormone)IBA
02/2024 - 07/2009
3abaloparatideIBA
11/2023 - 01/2022
3Calcitriol Receptors (Calcitriol Receptor)IBA
11/2023 - 06/2003
3Alendronate (Alendronate Sodium)FDA LinkGeneric
01/2022 - 06/2009
3Peptides (Polypeptides)IBA
01/2022 - 11/2005
3AlbuminsIBA
12/2021 - 02/2010
3RANK LigandIBA
01/2021 - 04/2006
3LigandsIBA
04/2020 - 01/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
04/2020 - 10/2003
3Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
01/2018 - 04/2010
3Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
12/2017 - 06/2004
325-hydroxyvitamin DIBA
01/2017 - 10/2014
3Anabolic AgentsIBA
10/2015 - 01/2008
3Teriparatide (Parathar)FDA Link
10/2014 - 01/2008
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2013 - 09/2005
3Dexamethasone (Maxidex)FDA LinkGeneric
06/2013 - 08/2007
3Adenosine Triphosphate (ATP)IBA
02/2012 - 04/2004
3Intravenous Immunoglobulins (IVIG)FDA Link
01/2010 - 06/2003
3GangliosidesIBA
01/2010 - 06/2003
3Chemokine CCL4IBA
04/2008 - 09/2002
3Alkaline PhosphataseIBA
01/2008 - 10/2004

Therapy/Procedure

29Therapeutics
03/2024 - 09/2002
4Transplantation
01/2012 - 10/2004
3Bed Rest (Bedrest)
07/2013 - 11/2004
3Immunotherapy
07/2011 - 01/2009
3Percutaneous Coronary Intervention
12/2010 - 02/2004
3Stents
10/2009 - 07/2003